
姓名:王艺凝
性别:女
籍贯:辽宁省辽阳市
联系电话:13936496840
E-Mail:wang.yi.ning@outlook.com
个人主页:
职称/职务:副教授
通讯地址:沈阳市沈河区文化路103号
邮政编码:110016
学习/工作经历:
2025.11-至今 沈阳药科大学 生命科学与生物制药学院
2023.10-2025.11 荷兰鹿特丹伊拉斯姆斯大学医学中心 博士后
2019.10-2023.09 荷兰鹿特丹伊拉斯姆斯大学医学中心 基础医学(病原生物学与免疫学) 博士
2016.09-2019.06 中国农业科学院兰州兽医研究所 预防兽医学 硕士
2011.09-2016.06 沈阳农业大学 动物医学 学士
研究方向:
1. 新发与再发病毒感染类器官-巨噬细胞共培养模型构建,解析病毒感染过程中的关键病理生理学特征;
2. 开发靶向炎症和病毒复制的新型抗病毒治疗方法, 探索病毒感染与免疫的发生机制与治疗靶点。
兼职情况:
科研/获奖情况:
教学/指导研究生情况:
发表论文/出版著作:
1. Macrophage-augmented organoids recapitulate the complex pathophysiology of viral diseases and devise advanced therapeutic strategies. Nature Biomedical Engineering. 2025 Nov;9(11):1848-1868. doi: 10.1038/s41551-025-01417-5. (co-first author)
2. AI-driven discovery of antiretroviral drug bictegravir and etravirine as inhibitors against monkeypox and related poxviruses. Commun Biol. 2025 Dec 2;8(1):1734. doi: 10.1038/s42003-025-09129-x. (First author)
3. Coronaviruses remodel the mature human tRNAome to modulate infection. Virulence. 2025 Dec;16(1):2580129. doi: 10.1080/21505594.2025.2580129. (First author)
4. Mpox: disease manifestations and therapeutic development. J Virol. 2025 Sep 23;99(9):e0015225. doi: 10.1128/jvi.00152-25. (First author)
5. Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response. iScience. 2023 Aug 16;26(9):107631. doi: 10.1016/j.isci.2023.107631. (First author)
6. Immunosuppressants exert differential effects on pan-coronavirus infection and distinct combinatory antiviral activity with molnupiravir and nirmatrelvir. United European Gastroenterol J. 2023 Jun;11(5):431-447. doi: 10.1002/ueg2.12417. (First author)
7. Seasonal coronavirus infections trigger NLRP3 inflammasome activation in macrophages but is therapeutically targetable. Antiviral Res. 2023 Aug;216:105674. doi: 10.1016/j.antiviral.2023.105674. (co-first author)
8. Nirmatrelvir exerts distinct antiviral potency against different human coronaviruses. Antiviral Res. 2023 Mar;211:105555. doi: 10.1016/j.antiviral.2023.105555. (co-first author)
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